History of Dental
Implants
Early Historical
Developments:
Replacing lost teeth with a
bone-anchored
device is not a new concept at all. Archeological findings showed that the ancient
Egyptian and South American civilizations already experimented with re-implanting
lost teeth with hand-shaped ivory or wood substitutes.
In the 18th century lost teeth
were sometimes replaced with extracted teeth of other human donors. The
implantation process was probably somewhat crude and the success rates extremely low due
to the strong immune reaction of the receiving individual.
In 1809, Maggiolo fabricated a
gold implant which was placed into fresh extraction sockets to which he attached
a tooth after a certain healing period. In 1887, a physician named Harris attempted the
same procedure with a platinum post, instead of a gold post. In 1886 Edmunds was the first
in the US to implant a platinum disc into the jawbone, to which a porcelain crown was
fixated. He demonstrated this at the First District Dental Society of New York. After
these initial steps, many other implantation attempts were made along the same lines,
experimenting with different metal alloys and porcelain formulations, however; on the
whole, the long-term success rates were still very poor.
Strock placed the first somewhat
successful oral implants in 1937 at Harvard University. Strock published a paper on the
physiological effects of cobalt-chromium-molybdenum alloy (vitallium) in bone, and thus
placed a series of vitallium implants into test animals and humans. These implants were
immediately implanted after an extraction of a tooth and no untoward post-operative
complications or reactions were recorded. Histologic sections from the test animals showed
a remarkable tissue tolerance to the vitallium implants. He followed some of his patients
successfully for over fifteen years, until he passed away. Certain types of implants used
today are often still cast from vitallium.
Modern Historical
Developments:
The time span from the mid-1930s
to the present represents the period in which certain implant concepts were developed,
which formed the foundation for today's variety of different implant modalities. These
modalities include the Subperiosteal, the Endosteal Blade, the Ramus
Frame and the Endosteal Root-form or Cylindrical Implant. These different implant types
or modalities are discussed in more detail in the Types of
Implants section.
The Subperiosteal
Implant has been a successful treatment for the past 30 years according to several
publications. The first Subperiosteal Implant was placed in 1948 by Gustav Dahl and was
constantly improved in its design since then.
The Endosteal
Blade Implant, introduced independently in 1967 by Leonard Linkow and Ralph and Harold
Roberts, also proved to be a very viable form of patient care with respect to implant
reconstruction.
The quantum leap in Oral
Implantology was achieved in 1952 in the Laboratory of Vital Microscopy at the University
of Lund, Sweden, by a Swedish research team headed by Per Ingvar Branemark, an Orthopedic
Surgeon. One of their research projects was to study the microscopic healing events
in bone. Their test subjects were rabbits. Dr. Branemark's team designed an optical
chamber housed in a titanium metal cylinder, which was screwed into the rabbit's
thighbone. Once the experiment was completed after several months, they realized that the
titanium cylinder had fused to the bone. He named this phenomenon Osseointegration. Based on this observation, Dr.
Branemark's research shifted more towards the use of titanium appliances in human bone,
including the use of titanium screws as bone anchors for lost teeth. Many experiments and
trials by himself and colleagues from other disciplines and institutions would head in
that direction providing adjunctive expertise in physics, chemistry, biomechanics,
medicine and physiology. The Osseointegration concept evolved closely coupled with the
design of a cylindrical titanium screw with a specific surface treatment to enhance its
bioacceptance.

On the left you can see what the
original Titanium Screw looked like.
Many animal and, subsequently,
human clinical trials were performed to test the success rate, the concept and the design
of this implant. Dr. Branemark battled the doubts of the scientific community for many
years with continuing clinical trials. In fact, it was not until 1981 when enough
long-term data was available to his team to publish a landmark paper for the scrutiny of
an intrigued scientific community.
In 1982, the Toronto Conference
on Osseointegration in Clinical Dentistry laid down the first parameters on what is to be
considered successful implant treatment within the stringent confines of the scientific
community. This Conference also catalyzed the acceptance and use of dental
implants in North America.
Since then many other foreign as
well as domestic implant systems have surfaced. Most of them are very similar in design to
the original Branemark Titanium Screw. However, many improvements have been made
since then by many different companies, and research continues to influence future designs
and concepts.
Although the FDA has been regulating all medical devices in the US since
1976, oral or dental implants have only recently been placed in a Class III (pre-market
approval) category. This will require the implant companies to furnish enough data from
controlled clinical and pre-clinical studies to satisfy the stringent restrictions of the
FDA, in order for their product to gain their full approval. This will ultimately enhance
marketing ethics and benefit the patients in terms of
a higher Standard of Care.